Liraglutide-13C5,15N TFA

• CAT Number: I040982
• Molecular Formula: C16713C5H265N4215NO51.xC2HF3O2
• Molecular Weight: 3757.16 (free acid)
• Purity: ≥95%

Liraglutide-13C5,15N (tetraTFA)is the 13C and 15N labeledLiraglutide(HY-P0014)[1]. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus[2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
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