For research use only. Not for therapeutic Use.
Lissamine rhodamine B is a red-fluorescent dye, it is a derivative of rhodamine. Lissamine rhodamine B can be used as a fluorescent probe to develop competitive aptamer fluorescence anisotropy/polarization (FA/FP) assays[1][2].
Lissamine rhodamine B (1 mg; 1 h; room temperature; dark) can be used to detect ochratoxin A (OTA) which is a common mycotoxin[1].
Lissamine rhodamine B have fluorescence properties, with the fluorescence detection conditions: excitation wavelength 555 nm, fluorescence emission spectrum detection 580 nm[1].
Lissamine rhodamine B can be used as an aradiotracer for imaging tumor mice by positron emission tomography (PET)[2].
| Catalog Number | I030862 |
| CAS Number | 2609-88-3 |
| Synonyms | 2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-sulfobenzenesulfonate |
| Molecular Formula | C27H30N2O7S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C27H30N2O7S2/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35) |
| InChIKey | IOOMXAQUNPWDLL-UHFFFAOYSA-N |
| SMILES | CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=C(C=C(C=C4)S(=O)(=O)O)S(=O)(=O)[O-] |
| Reference | [1]. Li Y, et al. Fluorescence Anisotropy-Based Signal-Off and Signal-On Aptamer Assays Using Lissamine Rhodamine B as a Label for Ochratoxin A. J Agric Food Chem. 2020 Apr 8;68(14):4277-4283. [2]. Li X, et al. The Synthesis and Evaluations of the (6 8) Ga-Lissamine Rhodamine B (LRB) as a New Radiotracer for Imaging Tumors by Positron Emission Tomography. Biomed Res Int. 2016;2016:8549635. |
