For research use only. Not for therapeutic Use.
Lodenafil carbonate(cas 398507-55-6) is a new PDE-5 inhibitor used for oral therapy in erectile dysfunction
Catalog Number | R058346 |
CAS Number | 398507-55-6 |
Synonyms | 5,5’-[Carbonylbis[oxy-2,1-ethanediyl-4,1-piperazinediylsulfonyl(6-ethoxy-3,1-phenylene)]]bis[1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidin-7-one; 4-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl] |
Molecular Formula | C47H62N12O11S2 |
Purity | 95% |
Target | Phosphodiesterase (PDE) |
Appearance | White Solid |
Storage | Store at -20°C |
IUPAC Name | bis[2-[4-[4-ethoxy-3-(1-methyl-7-oxo-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-5-yl)phenyl]sulfonylpiperazin-1-yl]ethyl] carbonate |
InChI | InChI=1S/C47H62N12O11S2/c1-7-11-35-39-41(54(5)52-35)45(60)50-43(48-39)33-29-31(13-15-37(33)67-9-3)71(63,64)58-21-17-56(18-22-58)25-27-69-47(62)70-28-26-57-19-23-59(24-20-57)72(65,66)32-14-16-38(68-10-4)34(30-32)44-49-40-36(12-8-2)53-55(6)42(40)46(61)51-44/h13-16,29-30H,7-12,17-28H2,1-6H3,(H,48,50,60)(H,49,51,61) |
InChIKey | MVYUCRDXZXLFSB-UHFFFAOYSA-N |
SMILES | CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)CCOC(=O)OCCN5CCN(CC5)S(=O)(=O)C6=CC(=C(C=C6)OCC)C7=NC(=O)C8=C(N7)C(=NN8C)CCC)OCC)C |
Reference | 1: Codevilla CF, Castilhos Tdos S, Cirne CA, Froehlich PE, Bergold AM. 2: Nunes LV, Lacaz FS, Bressan RA, Nunes SO, Mari Jde J. Adjunctive treatment 3: Mendes GD, dos Santos Filho HO, dos Santos Pereira A, Mendes FD, Ilha JO, 4: Codevilla CF, Lemos AM, Delgado LS, Rolim CM, Adams AI, Bergold AM. 5: Silva AC, Toffoletto O, Lucio LA, Santos PF, Afiune JB, Massud Filho J, Tufik 6: Glina S, Fonseca GN, Bertero EB, Damião R, Rocha LC, Jardim CR, Cairoli CE, 7: Glina S, Toscano I, Gomatzky C, de Góes PM, Júnior AN, Claro JF, Pagani E. 8: Toque HA, Teixeira CE, Lorenzetti R, Okuyama CE, Antunes E, De Nucci G. |