For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Lofexidine hydrochloride (Cat.No:I002649) is an α2A-adrenergic receptor agonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.</p>
| Catalog Number | I002649 |
| CAS Number | 21498-08-8 |
| Synonyms | 2-[1-(2,6-dichlorophenoxy)ethyl]-4,5-dihydro-1H-imidazole, monohydrochloride |
| Molecular Formula | C11H12Cl2N2O • HCl |
| Purity | ≥95% |
| Target | Adrenergic Receptor |
| Solubility | 10 mM in H2O |
| Storage | Store at -20°C |
| InChIKey | DWWHMKBNNNZGHF-UHFFFAOYSA-N |
| Reference | </br>1:Pharmacokinetics of lofexidine hydrochloride in healthy volunteers. Al-Ghananeem AM.J Pharm Sci. 2009 Jan;98(1):319-26. doi: 10.1002/jps.21401. PMID: 18393298 </br>2:Randomized placebo controlled trial of lofexidine hydrochloride for chronic pelvic pain in women. Stones RW, Bradbury L, Anderson D.Hum Reprod. 2001 Aug;16(8):1719-21. PMID: 11473971 </br>3:The absorption and excretion of 14C-lofexidine hydrochloride in man. Midgley I, Chasseaud LF, Taylor T, Darragh A.Arzneimittelforschung. 1982;32(8a):972-5. No abstract available. PMID: 6890372 |
