For research use only. Not for therapeutic Use.
Loncastuximab tesirine（Cat No.:I042242）is an antibody-drug conjugate (ADC) designed for the treatment of cancers, particularly relapsed or refractory B-cell lymphomas. It combines an anti-CD19 monoclonal antibody with a potent cytotoxic drug, pyrrolobenzodiazepine dimer, which is released inside cancer cells upon binding to CD19, a protein expressed on the surface of B-cells. This targeted approach allows for the selective delivery of the cytotoxic agent to cancer cells, minimizing damage to healthy cells. Loncastuximab tesirine has shown promising results in clinical trials and is being explored for use in other CD19-positive cancers.
| CAS Number | 1879918-31-6 |
| Purity | ≥95% |
