Lopinavir-d8

• CAT Number: R005328
• CAS Number: 1322625-54-6
• Molecular Formula: C37H48N4O5
• Molecular Weight: 636.863
• Purity: ≥95%
• Synonyms: (αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide-?d8; A 157378.0-d8; ABT 378-d8; Aluviran-d8; Koletra-d8
• Storage: Store at -20°C
• IUPAC Name: 2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
• InChI: InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34?/m0/s1/i1D3,2D3,25D,34D
• InChIKey: KJHKTHWMRKYKJE-JOYHXWCXSA-N
• SMILES: CC1=C(C(=CC=C1)C)OCC(=O)NC(CC2=CC=CC=C2)C(CC(CC3=CC=CC=C3)NC(=O)C(C(C)C)N4CCCNC4=O)O

Lopinavir-d8 is a deuterated antiretroviral medication used in HIV research. This compound, labeled with eight deuterium atoms, provides enhanced stability and precise analytical results. Lopinavir-d8 is crucial for pharmacokinetic studies, enabling researchers to track the drug’s metabolism and distribution accurately. Its stable isotope labeling minimizes background noise, ensuring reliable data in clinical and laboratory settings. Ideal for advanced pharmaceutical research, Lopinavir-d8 supports the development of effective HIV treatments by offering a robust and precise tool for scientific investigations.