Lopinavir N2,N5-Divalinate Impurity-d8

• CAT Number: R029691
• CAS Number: NA
• Molecular Formula: C₃₆H₄₄D₈N₆O₅
• Molecular Weight: 656.88
• Purity: ≥95%
• Synonyms: (2S,2’S)-N,N’-((2S,3S,5S)-3-Hydroxy-1,6-diphenylhexane-2,5-diyl)bis(3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanamide)-d8
• Storage: Store at -20°C
• IUPAC Name: (2R)-2,3,4,4,4-pentadeuterio-N-[(2S,4S,5S)-4-hydroxy-5-[[(2S)-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanoyl]amino]-1,6-diphenylhexan-2-yl]-2-(2-oxo-1,3-diazinan-1-yl)-3-(trideuteriomethyl)butanamide
• InChI: InChI=1S/C36H52N6O5/c1-24(2)31(41-19-11-17-37-35(41)46)33(44)39-28(21-26-13-7-5-8-14-26)23-30(43)29(22-27-15-9-6-10-16-27)40-34(45)32(25(3)4)42-20-12-18-38-36(42)47/h5-10,13-16,24-25,28-32,43H,11-12,17-23H2,1-4H3,(H,37,46)(H,38,47)(H,39,44)(H,40,45)/t28-,29-,30-,31+,32-/m0/s1/i1D3,2D3,24D,31D
• InChIKey: OIPWRPUYYJNJRT-RDHPMIJMSA-N
• SMILES: CC(C)C(C(=O)NC(CC1=CC=CC=C1)CC(C(CC2=CC=CC=C2)NC(=O)C(C(C)C)N3CCCNC3=O)O)N4CCCNC4=O

Lopinavir N2, N5-Divalinate Impurity-d8（Cat No.:R029691） is a deuterated form of a specific impurity found in the synthesis or degradation of Lopinavir, where eight hydrogen atoms are replaced with deuterium. This isotopic labeling enhances the impurity’s stability and makes it highly useful for analytical purposes, particularly in mass spectrometry and NMR spectroscopy. Lopinavir is an antiretroviral medication used primarily for the treatment of HIV/AIDS. Studying this deuterated impurity helps in understanding the stability, pharmacokinetics, and potential toxicology of Lopinavir, ensuring the efficacy and safety of the medication in clinical use.