For research use only. Not for therapeutic Use.
Loracarbef hydrate, a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].
Loracarbef hydrate demonstrates excellent activity against isolates of Escherichia coli and Klebsiella, Proteus and Salmonella species[2].
| Catalog Number | M016011 |
| CAS Number | 121961-22-6 |
| Synonyms | (6R,7S)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;hydrate |
| Molecular Formula | C16H18ClN3O5 |
| Purity | ≥95% |
| InChI | InChI=1S/C16H16ClN3O4.H2O/c17-9-6-7-10-12(15(22)20(10)13(9)16(23)24)19-14(21)11(18)8-4-2-1-3-5-8;/h1-5,10-12H,6-7,18H2,(H,19,21)(H,23,24);1H2/t10-,11-,12+;/m1./s1 |
| InChIKey | GPYKKBAAPVOCIW-HSASPSRMSA-N |
| SMILES | C1CC(=C(N2C1C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)O)Cl.O |
| Reference | [1]. M Hu, et al. Mechanisms of Transport of Quinapril in Caco-2 Cell Monolayers: Comparison With Cephalexin. Pharm Res. 1995 Aug;12(8):1120-5. [2]. J W Dyke, et al. Antimicrobial Activity of New Antibiotics Against Bacterial Isolates From a Community Hospital. Chemotherapy. Sep-Oct 1993;39(5):315-21. |
