For research use only. Not for therapeutic Use.
(S)-Lorazepam acetate(CAT: I030996) is the acetate ester form of the (S)-enantiomer of Lorazepam, a benzodiazepine derivative known for its potent anxiolytic, sedative, anticonvulsant, and muscle relaxant properties. Like Lorazepam, it likely acts as a positive allosteric modulator of the GABAA receptor, enhancing the effect of gamma-aminobutyric acid (GABA), the brain’s primary inhibitory neurotransmitter. This action increases neuronal inhibition, resulting in calming effects. The acetate form may improve solubility or pharmacokinetics, making it potentially useful in pharmaceutical research for developing treatments for anxiety, insomnia, and seizure disorders.
Catalog Number | I030996 |
CAS Number | 84799-34-8 |
Synonyms | Lorazepam acetate, (S)-; (-)-Lorazepam acetate; (S)-Lorazepam acetate; L-Lorazepam acetate; |
Molecular Formula | C17H12Cl2N2O3 |
Purity | 98% |
Solubility | Soluble in DMSO |
Appearance | Solid powder |
Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
IUPAC Name | (S)-7-chloro-5-(2-chlorophenyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl acetate |
InChI | InChI=1S/C17H12Cl2N2O3/c1-9(22)24-17-16(23)20-14-7-6-10(18)8-12(14)15(21-17)11-4-2-3-5-13(11)19/h2-8,17H,1H3,(H,20,23)/t17-/m0/s1 |
InChIKey | CYDZMDOLVUBPNL-KRWDZBQOSA-N |
SMILES | O=C1NC2=CC=C(Cl)C=C2C(C3=CC=CC=C3Cl)=N[C@H]1OC(C)=O |