For research use only. Not for therapeutic Use.
Lotiglipron(CAT: I040912) is an oral selective inhibitor of pancreatic lipase, an enzyme responsible for the breakdown of dietary fats in the gastrointestinal tract. By inhibiting this enzyme, Lotiglipron reduces the digestion and absorption of fats, leading to a decrease in fat storage and potentially aiding in weight management. Additionally, it has shown promise in improving lipid profiles and reducing body fat in clinical trials. Lotiglipron could be explored for research in the context of metabolic disease, particularly for obesity and related disorders like type 2 diabetes. It is relevant for Metabolic Disease Research, with potential applications in managing obesity and dyslipidemia.
| CAS Number | 2401892-75-7 |
| Synonyms | 2-[[4-[(2S)-2-(5-chloropyridin-2-yl)-2-methyl-1,3-benzodioxol-4-yl]piperidin-1-yl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic acid |
| Molecular Formula | C31H31ClN4O5 |
| Purity | ≥95% |
| IUPAC Name | 2-[[4-[(2S)-2-(5-chloropyridin-2-yl)-2-methyl-1,3-benzodioxol-4-yl]piperidin-1-yl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic acid |
| InChI | InChI=1S/C31H31ClN4O5/c1-31(27-8-6-21(32)16-33-27)40-26-4-2-3-23(29(26)41-31)19-9-12-35(13-10-19)18-28-34-24-7-5-20(30(37)38)15-25(24)36(28)17-22-11-14-39-22/h2-8,15-16,19,22H,9-14,17-18H2,1H3,(H,37,38)/t22-,31-/m0/s1 |
| InChIKey | SVPYZAJTWFQTSM-UGDMGKLASA-N |
| SMILES | C[C@@]1(OC2=CC=CC(=C2O1)C3CCN(CC3)CC4=NC5=C(N4C[C@@H]6CCO6)C=C(C=C5)C(=O)O)C7=NC=C(C=C7)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
