For research use only. Not for therapeutic Use.
Loviride(Cat No.:M093940)is a non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment of HIV-1 infections. It binds to reverse transcriptase, causing conformational changes that inhibit the enzyme’s function, thereby preventing viral RNA replication. Loviride has demonstrated antiviral activity and was explored as a potential addition to combination therapies for managing HIV. Although no longer widely used clinically, it remains a valuable compound in HIV research for studying NNRTI mechanisms, resistance patterns, and the development of next-generation therapies aimed at improving antiretroviral treatment outcomes.
Catalog Number | M093940 |
CAS Number | 147362-57-0 |
Synonyms | Loviride |
Molecular Formula | C17H16Cl2N2O2 |
Purity | ≥95% |
Target | Reverse Transcriptase |
Storage | Desiccate at +4C |
IUPAC Name | 2-(2-acetyl-5-methylanilino)-2-(2,6-dichlorophenyl)acetamide |
InChI | InChI=1S/C17H16Cl2N2O2/c1-9-6-7-11(10(2)22)14(8-9)21-16(17(20)23)15-12(18)4-3-5-13(15)19/h3-8,16,21H,1-2H3,(H2,20,23) |
InChIKey | CJPLEFFCVDQQFZ-UHFFFAOYSA-N |
SMILES | CC1=CC(=C(C=C1)C(=O)C)NC(C2=C(C=CC=C2Cl)Cl)C(=O)N |