For research use only. Not for therapeutic Use.
LpxC-IN-10 (Compound A) is a high selectivity inhibitor of LpxC. LpxC-IN-10 exhibits MIC values of 0.5 μg/mL against E. coli and K. pneumoniae. LpxC-IN-10 (Compound A) can be used for the research of bacterial infection[1]. LpxC-IN-10 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
LpxC-IN-10 (Compound A) shows a MIC value of 0.5 μg/mL to E. coli and K. pneumoniae[1].
| Catalog Number | I043425 |
| CAS Number | 2413574-64-6 |
| Synonyms | 1-[(2S)-3-(5-hydroxy-6-oxo-1H-pyrimidin-4-yl)-2-[4-[2-[4-(morpholin-4-ylmethyl)phenyl]ethynyl]phenyl]propyl]azetidine-3-carbonitrile |
| Molecular Formula | C30H31N5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C30H31N5O3/c31-16-25-18-35(19-25)20-27(15-28-29(36)30(37)33-21-32-28)26-9-7-23(8-10-26)2-1-22-3-5-24(6-4-22)17-34-11-13-38-14-12-34/h3-10,21,25,27,36H,11-15,17-20H2,(H,32,33,37)/t27-/m1/s1 |
| InChIKey | RVSQDMFHNYKDPF-HHHXNRCGSA-N |
| SMILES | C1COCCN1CC2=CC=C(C=C2)C#CC3=CC=C(C=C3)C(CC4=C(C(=O)NC=N4)O)CN5CC(C5)C#N |
| Reference | [1]. Min T, et al. LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF:, US20210315902A1[P]. 2021. |
