For research use only. Not for therapeutic Use.
LSL60101 is a selective imidazoline2 (I2) receptor ligand with KiH and KiL values of 350 nM and 116 μM, respectively. LSL 60101 plays a neuroprotective role by reducing apoptosis and modulating oxidative stress.
KEYWORDS: LSL60101 | Supplier | I2 ligand | Garsevil | LSL 60101 | LSL-60101 | CAS [150985-54-9] | [150985-44-7] | Imidazoline | I2 | Ligand | Receptors | Neuronal regeneration | Alzheimer’s disease | Neuroprotection | Oxidative stress
| Catalog Number | I031054 |
| CAS Number | 150985-54-9 |
| Molecular Formula | C11H8N2O |
| Purity | ≥95% |
| IUPAC Name | 2-(1-benzofuran-2-yl)-1H-imidazole |
| InChI | InChI=1S/C11H8N2O/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11/h1-7H,(H,12,13) |
| SMILES | C1=CC=C2C(=C1)C=C(O2)C3=NC=CN3 |
| Reference | R Alemany et al. LSL 60101, a selective ligand for imidazoline I2 receptors, on glial fibrillary acidic protein concentration. Eur J Pharmacol. 1995 Jul 4;280(2):205-10. S Rodriguez-Arévalo et al. Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer’s disease. Eur J Med Chem. 2021 Oct 15;222:113540. |
