LSN3318839

For research use only. Not for therapeutic Use.

  • CAT Number: I045215
  • CAS Number: 2764704-18-7
  • Molecular Formula: C26H23Cl2N3O2
  • Molecular Weight: 480.39
  • Purity: ≥95%
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LSN3318839 is an orally efficacious positive allosteric modulator of the glucagon-like peptide-1 receptor (GLP-1R).


Catalog Number I045215
CAS Number 2764704-18-7
Synonyms

(2R)-2-[2-[1-[(1R)-1-(2,6-dichloro-3-cyclopropylphenyl)ethyl]imidazo[4,5-c]pyridin-6-yl]phenyl]propanoic acid

Molecular Formula C26H23Cl2N3O2
Purity ≥95%
InChI InChI=1S/C26H23Cl2N3O2/c1-14(26(32)33)17-5-3-4-6-19(17)21-11-23-22(12-29-21)30-13-31(23)15(2)24-20(27)10-9-18(25(24)28)16-7-8-16/h3-6,9-16H,7-8H2,1-2H3,(H,32,33)/t14-,15-/m1/s1
InChIKey JPJWHCNGSBCZMI-HUUCEWRRSA-N
SMILES CC(C1=CC=CC=C1C2=NC=C3C(=C2)N(C=N3)C(C)C4=C(C=CC(=C4Cl)C5CC5)Cl)C(=O)O
Reference

[1]. Willard FS, et al. Discovery of an Orally Efficacious Positive Allosteric Modulator of the Glucagon-like Peptide-1 Receptor. J Med Chem. 2021 Mar 25;64(6):3439-3448.
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