Lumateperone PTSA salt

• CAT Number: I007735
• CAS Number: 1187020-80-9 (PTSA salt); 313368-91-1 (free base).
• Molecular Formula: C31H36FN3O4S
• Molecular Weight: 565.7044
• Purity: ≥95%
• Synonyms: ITI-722; ITI722; ITI 722; ITI-007; ITI007; ITI 007; Lumateperone, CAS#313368-91-1;1-(4-fluorophenyl)-4-[(6bR,10aS)-3-methyl-2,3,6b,9,10,10a-hexahydro-1H-pyrido[3/’,4/’:4,5]pyrrolo[1,2,3-de]quinoxalin-8(7H)-yl]butan-1-one toluenesulfonic acid
• Target: 5HT2A antagonist
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4°C for short term , or -20°C for long term.
• SMILES: O=C(C1=CC=C(F)C=C1)CCCN2CC[C@@](N3CCN(C)C4=C3C5=CC=C4)([H])[C@@]5([H])C2.CC6=CC=C(S(=O)(O)=O)C=C6

Lumateperone toluenesulfonic acid or Lumateperone PTSA salt, also known as ITI-722 or ITI-007, is a highly potent 5HT2A antagonist for the treatment of sleep maintenance insomnia. Preclinical data has shown that ITI-722 is not sedating and should not exhibit next day hangover effects that are commonly associated with other sleep medications. ITI-722 is expected to have a strong safety profile with no addiction liability.