lumateperone Tosylate

• CAT Number: I000670
• CAS Number: 1187020-80-9
• Molecular Formula: C31H36FN3O4S
• Molecular Weight: 565.70
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: 10 mM in DMSO
• Storage: Store at -20°C
• IC50: 0.54 nM (Ki, for 5-HT2A receptor )
• IUPAC Name: 1-(4-fluorophenyl)-4-[(10R,15S)-4-methyl-1,4,12-triazatetracyclo[7.6.1.05,16.010,15]hexadeca-5,7,9(16)-trien-12-yl]butan-1-one;4-methylbenzenesulfonic acid
• InChI: InChI=1S/C24H28FN3O.C7H8O3S/c1-26-14-15-28-21-11-13-27(16-20(21)19-4-2-5-22(26)24(19)28)12-3-6-23(29)17-7-9-18(25)10-8-17;1-6-2-4-7(5-3-6)11(8,9)10/h2,4-5,7-10,20-21H,3,6,11-16H2,1H3;2-5H,1H3,(H,8,9,10)/t20-,21-;/m0./s1
• InChIKey: LHAPOGAFBLSJJQ-GUTACTQSSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CN1CCN2[C@H]3CCN(C[C@H]3C4=C2C1=CC=C4)CCCC(=O)C5=CC=C(C=C5)F

Lumateperone tosylate（Cat No.:I000670）is the tosylate salt form of lumateperone, an atypical antipsychotic medication used primarily for the treatment of schizophrenia and bipolar disorder. Lumateperone works by modulating various neurotransmitter systems, including dopamine, serotonin, and glutamate, helping to balance neurotransmission in the brain. It is known for its favorable side-effect profile compared to other antipsychotics, with less sedation and weight gain. Lumateperone has demonstrated efficacy in improving both positive and negative symptoms of schizophrenia, making it a promising option for managing psychotic disorders with fewer adverse effects.