Lumefantrine-d9

For research use only. Not for therapeutic Use.

  • CAT Number: S000188
  • CAS Number: 2477594-24-2
  • Molecular Formula: C30H23D9Cl3NO
  • Molecular Weight: 538
  • Purity: ≥95%
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Lumefantrine-d9 (CAS: 2477594-24-2), a premium pharmaceutical research compound designed for advanced antimalarial studies. As a deuterated analog of Lumefantrine, it offers enhanced stability and improved pharmacokinetic properties. Lumefantrine-d9 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel therapies for malaria. Trusted by leading laboratories, Lumefantrine-d9 is your go-to solution for cutting-edge antimalarial research. Unlock new possibilities in malaria treatment with Lumefantrine-d9, where innovation meets reliability.


Catalog Number S000188
CAS Number 2477594-24-2
Molecular Formula C30H23D9Cl3NO
Purity ≥95%
IUPAC Name 2-[butyl(1,1,2,2,3,3,4,4,4-nonadeuteriobutyl)amino]-1-[(9Z)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol
InChI InChI=1S/C30H32Cl3NO/c1-3-5-13-34(14-6-4-2)19-29(35)28-18-23(33)17-27-25(15-20-7-9-21(31)10-8-20)26-16-22(32)11-12-24(26)30(27)28/h7-12,15-18,29,35H,3-6,13-14,19H2,1-2H3/b25-15-/i1D3,3D2,5D2,13D2
InChIKey DYLGFOYVTXJFJP-BWOMUDRSSA-N
SMILES [2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])N(CCCC)CC(C1=CC(=CC\2=C1C3=C(/C2=C/C4=CC=C(C=C4)Cl)C=C(C=C3)Cl)Cl)O
Reference

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[Content Brief]

[2]. Ndounga M, et al. Artesunate-amodiaquine versus artemether-lumefantrine for the treatment of acute uncomplicated malaria in Congolese children under 10 years old living in a suburban area: a randomized study. Malar J. 2015 Oct 29;14(1):423.
[Content Brief]

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