Luminol Sodium Salt

• CAT Number: M002606
• CAS Number: 20666-12-0
• Molecular Formula: C8H6N3NaO2
• Molecular Weight: 199.14
• Purity: ≥95%
• Synonyms: SODIUM LUMINOL;5-amino-2,3-dihydro-1,4-*phthalazinedionesodium;LUMINOL SODIUM SALT HG;LUMINOL SODIUM SALT;3-AMINOPHTHALHYDRAZIDE MONOSODIUM SALT;3-AMINOPHTHALHYDRAZIDE SODIUM SALT;5-AMINO-2,3-DIHYDRO-1,4-PHTHALAZINEDIONE SODIUM SALT;Luminol monosodiu
• Storage: Store at -20C
• IUPAC Name: sodium;8-amino-2H-phthalazin-3-ide-1,4-dione
• InChI: InChI=1S/C8H7N3O2.Na/c9-5-3-1-2-4-6(5)8(13)11-10-7(4)12;/h1-3H,9H2,(H,10,12)(H,11,13)
• InChIKey: JKEBMURXLKGPLR-UHFFFAOYSA-N
• SMILES: C1=CC2=C(C(=C1)N)C(=O)NNC2=O.[Na]

Luminol Sodium Salt (CAS 20666-12-0) is used for chemiluminescence analysis of, for example, metal cations, blood and glucococorticoids. Luminol sodium salt has also been used in vivo to image myeloperoxidase activity.

Reference

1.Gross, Shimon, et al. "Bioluminescence imaging of myeloperoxidase activity in vivo." Nature medicine 15.4 (2009): 455.
2.Madeira, Jocelyn M., et al. "Gold drug auranofin could reduce neuroinflammation by inhibiting microglia cytotoxic secretions and primed respiratory burst." Journal of neuroimmunology 276.1-2 (2014): 71-79.
3.Zhang, Yunjia, et al. "Selenomethionine supplementation reduces lesion burden, improves vessel function and modulates the inflammatory response within the setting of atherosclerosis." Redox biology 29 (2020): 101409.
4.Gross, Shimon, et al. "Bioluminescence imaging of myeloperoxidase activity in vivo." Nature medicine 15.4 (2009): 455.
5.Kimura, Sachie, et al. "CRK2 and C-terminal phosphorylation of NADPH oxidase RBOHD regulate reactive oxygen species production in Arabidopsis." The Plant Cell 32.4 (2020): 1063-1080.