For research use only. Not for therapeutic Use.
LY 181984 is an antitumor sulfonylurea.
| Catalog Number | I007769 |
| CAS Number | 3955-50-8 |
| Synonyms | LY 181984; LY-181984; LY181984; MPCU.;Benzenesulfonamide, N-(((4-chlorophenyl)amino)carbonyl)-4-methyl- |
| Molecular Formula | C14H13ClN2O3S |
| Purity | ≥95% |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4°C for short term , or -20°C for long term. |
| IUPAC Name | 1-(4-chlorophenyl)-3-(4-methylphenyl)sulfonylurea |
| InChI | InChI=1S/C14H13ClN2O3S/c1-10-2-8-13(9-3-10)21(19,20)17-14(18)16-12-6-4-11(15)5-7-12/h2-9H,1H3,(H2,16,17,18) |
| InChIKey | YOIDHZBOHMNTNP-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2=CC=C(C=C2)Cl |
| Reference | </br>1:Chueh PJ, Kim C, Cho N, Morré DM, Morré DJ. Molecular cloning and characterization of a tumor-associated, growth-related, and time-keeping hydroquinone (NADH) oxidase (tNOX) of the HeLa cell surface. Biochemistry. 2002 Mar 19;41(11):3732-41. PubMed PMID: 11888291.</br>2:Morré DJ, Chueh PJ, Lawler J, Morré DM. The sulfonylurea-inhibited NADH oxidase activity of HeLa cell plasma membranes has properties of a protein disulfide-thiol oxidoreductase with protein disulfide-thiol interchange activity. J Bioenerg Biomembr. 1998 Oct;30(5):477-87. PubMed PMID: 9932650. |
