LY 181984

• CAT Number: I007769
• CAS Number: 3955-50-8
• Molecular Formula: C14H13ClN2O3S
• Molecular Weight: 324.78
• Purity: ≥95%
• Synonyms: LY 181984; LY-181984; LY181984; MPCU.;Benzenesulfonamide, N-(((4-chlorophenyl)amino)carbonyl)-4-methyl-
• Solubility: Soluble in DMSO
• Storage: 0 - 4°C for short term , or -20°C for long term.
• IUPAC Name: 1-(4-chlorophenyl)-3-(4-methylphenyl)sulfonylurea
• InChI: InChI=1S/C14H13ClN2O3S/c1-10-2-8-13(9-3-10)21(19,20)17-14(18)16-12-6-4-11(15)5-7-12/h2-9H,1H3,(H2,16,17,18)
• InChIKey: YOIDHZBOHMNTNP-UHFFFAOYSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NC2=CC=C(C=C2)Cl

LY 181984（Cat No.:I007769）is a selective, small molecule inhibitor of protein kinase C (PKC), specifically targeting the PKCα and PKCβ isoforms. PKC enzymes play a key role in various cellular processes such as signal transduction, cell proliferation, differentiation, and apoptosis. By inhibiting these isoforms, LY 181984 is used in research to investigate the role of PKC in diseases like cancer, cardiovascular disorders, and autoimmune conditions. It helps explore the therapeutic potential of PKC inhibition, particularly in the treatment of abnormal cell growth and inflammation. LY 181984 is primarily used in preclinical studies.