For research use only. Not for therapeutic Use.
LY 294002 hydrochloride(Cat No.:I010373)is a potent, selective inhibitor of phosphoinositide 3-kinase (PI3K), a key enzyme in the PI3K/Akt signaling pathway that regulates cell growth, survival, and metabolism. By inhibiting PI3K, LY 294002 hydrochloride blocks downstream signaling, leading to reduced cell proliferation and increased apoptosis, making it a valuable compound in cancer research. It is widely used to study the role of PI3K in various diseases, including cancer, diabetes, and neurodegenerative disorders. Its hydrochloride form enhances solubility, making it more suitable for in vitro and in vivo studies.
Catalog Number | I010373 |
CAS Number | 934389-88-5 |
Synonyms | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
Molecular Formula | C19H18ClNO3 |
Purity | ≥95% |
Target | Stem Cell/Wnt |
Solubility | Soluble to 25 mM in DMSO and to 5 mM in ethanol |
Storage | Store at RT |
IUPAC Name | 2-morpholin-4-yl-8-phenylchromen-4-one;hydrochloride |
InChI | InChI=1S/C19H17NO3.ClH/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14;/h1-8,13H,9-12H2;1H |
InChIKey | OQZQSRICUOWBLW-UHFFFAOYSA-N |
SMILES | C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4.Cl |