For research use only. Not for therapeutic Use.
LY-411575 isomer 1 is an isomer of LY411575, which is a potent γ-secretase inhibitor.
| Catalog Number | I002615 |
| CAS Number | 209984-58-7 |
| Synonyms | (2S)-2-[[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide |
| Molecular Formula | C26H23F2N3O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H23F2N3O4/c1-14(29-25(34)23(32)15-11-16(27)13-17(28)12-15)24(33)30-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)31(2)26(22)35/h3-14,22-23,32H,1-2H3,(H,29,34)(H,30,33)/t14-,22-,23+/m0/s1 |
| InChIKey | ULSSJYNJIZWPSB-AETJINEWSA-N |
| SMILES | CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)C(C4=CC(=CC(=C4)F)F)O |
| Reference | [1]. Fauq AH, et al. A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6392-5. Epub 2007 Aug 30. |
