For research use only. Not for therapeutic Use.
LY 78335(CAT: I010885) is a high-affinity inhibitor of phenylethanolamine-N-methyltransferase (PNMT). PNMT is an enzyme involved in the conversion of norepinephrine to epinephrine, a process important in the synthesis of catecholamines. By inhibiting PNMT, LY 78335 can block the activity of this enzyme and potentially reduce the production of epinephrine. In an in vivo rat model, LY 78335 has been shown to suppress the release of growth hormone.
| Catalog Number | I010885 |
| CAS Number | 39959-66-5 |
| Synonyms | 2,3-Dichloro-α-methylbenzylamine hydrochloride |
| Molecular Formula | C8H10Cl3N |
| Purity | ≥95% |
| Target | Transferase |
| Solubility | Soluble to 100 mM in water with gentle warming and to 100 mM in DMSO with gentle warming |
| Storage | Desiccate at RT |
| IUPAC Name | 1-(2,3-dichlorophenyl)ethanamine;hydrochloride |
| InChI | InChI=1S/C8H9Cl2N.ClH/c1-5(11)6-3-2-4-7(9)8(6)10;/h2-5H,11H2,1H3;1H |
| InChIKey | FQTXPVLCCDQRHY-UHFFFAOYSA-N |
| SMILES | CC(C1=C(C(=CC=C1)Cl)Cl)N.Cl |
