LY177206

For research use only. Not for therapeutic Use.

  • CAT Number: I031201
  • CAS Number: 127026-22-6
  • Molecular Formula: C15H15NO
  • Molecular Weight: 225.29
  • Purity: 98%
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LY177206(Cat No.:I031201)is a selective antagonist of the neurokinin-1 (NK1) receptor, a receptor involved in the transmission of pain and inflammation through the substance P neuropeptide. By blocking this receptor, LY177206 has been studied for its potential to reduce pain and inflammation, making it a candidate for treating conditions such as chronic pain, migraines, and anxiety disorders. It has also shown promise in preventing nausea and vomiting associated with chemotherapy. Though it has demonstrated efficacy in preclinical and early clinical trials, further research is needed to fully establish its therapeutic potential and safety profile.


Catalog Number I031201
CAS Number 127026-22-6
Synonyms

LY177206; LY-177206; LY 177206

Molecular Formula C15H15NO
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 1-(2-methylbutan-2-yl)-3-oxoindene-2-carbonitrile
InChI InChI=1S/C15H15NO/c1-4-15(2,3)13-10-7-5-6-8-11(10)14(17)12(13)9-16/h5-8H,4H2,1-3H3
InChIKey WWXYVYUCPQOVAM-UHFFFAOYSA-N
SMILES CCC(C)(C)C1=C(C(=O)C2=CC=CC=C21)C#N

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