For research use only. Not for therapeutic Use.
LY2780301 is a highly selective adenosine triphosphate (ATP)-competitive dual inhibitor of p70S6K and Akt. LY2780301 binds to Akt, inhibiting its activity, which consequently blocks the PI3K/Akt signaling pathway which leads to reduced cell proliferation and the initiation of apoptosis in tumor cells.
| Catalog Number | I047339 |
| CAS Number | 1226801-23-5 |
| Molecular Formula | C25H27F4N7O |
| Purity | ≥95% |
| Reference | [1] Azaro A, et al. Invest New Drugs. 2015 Jun;33(3):710-9. |
