For research use only. Not for therapeutic Use.
LY3537982 (KRAS G12C inhibitor 19) is a highly selective and potent inhibitor of the KRAS-G12C protein. LY3537982 selectively inhibits the growth of KRAS G12C mutant cells H23 G12C, H358 G12C, and H2122 G12C with IC50s of 1.04 nM, 1.16 nM, and 11.38 nM, respectively.
| Catalog Number | I047341 |
| CAS Number | 2649788-46-3 |
| Molecular Formula | C25H19ClF2N4O3S |
| Purity | ≥95% |
| Reference | [1] Palma G, et al. NPJ Precis Oncol. 2021 Nov 29;5(1):98. |
