For research use only. Not for therapeutic Use.
LY392098 is a AMPA receptor potentiator.
| Catalog Number | I007850 |
| CAS Number | 211311-39-6 |
| Synonyms | LY392098; LY 392098; LY-392098.;N-{2-[4-(2-fluorophenyl)phenyl]propyl}propane-2-sulfonamide |
| Molecular Formula | C18H22FNO2S |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble in DMSO |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| InChI | InChI=1S/C18H22FNO2S/c1-13(2)23(21,22)20-12-14(3)15-8-10-16(11-9-15)17-6-4-5-7-18(17)19/h4-11,13-14,20H,12H2,1-3H3 |
| InChIKey | CECANHFDVPUVMI-UHFFFAOYSA-N |
| SMILES | CC(S(=O)(NCC(C1=CC=C(C2=CC=CC=C2F)C=C1)C)=O)C |
| Reference | </br>1:Antidepressant-like actions of an AMPA receptor potentiator (LY392098). Li X, Tizzano JP, Griffey K, Clay M, Lindstrom T, Skolnick P.Neuropharmacology. 2001 Jun;40(8):1028-33. PMID: 11406194 </br>2:Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator. Legutko B, Li X, Skolnick P.Neuropharmacology. 2001 Jun;40(8):1019-27. PMID: 11406193 </br>3:Potentiation of responses to AMPA on central neurones by LY392098 and LY404187 in vivo. Vandergriff J, Huff K, Bond A, Lodge D.Neuropharmacology. 2001 Jun;40(8):1003-9. PMID: 11406191 </br>4:LY392098, a novel AMPA receptor potentiator: electrophysiological studies in prefrontal cortical neurons. Baumbarger P, Muhlhauser M, Yang CR, Nisenbaum ES.Neuropharmacology. 2001 Jun;40(8):992-1002. PMID: 11406190 </br>5:Pharmacological effects of AMPA receptor potentiators LY392098 and LY404187 on rat neuronal AMPA receptors in vitro. Gates M, Ogden A, Bleakman D.Neuropharmacology. 2001 Jun;40(8):984-91. PMID: 11406189 </br>6:Novel AMPA receptor potentiators LY392098 and LY404187: effects on recombinant human AMPA receptors in vitro. Miu P, Jarvie KR, Radhakrishnan V, Gates MR, Ogden A, Ornstein PL, Zarrinmayeh H, Ho K, Peters D, Grabell J, Gupta A, Zimmerman DM, Bleakman D.Neuropharmacology. 2001 Jun;40(8):976-83. PMID: 11406188 |
