LYCOCTONINE

• CAT Number: T000013
• CAS Number: 26000-17-9
• Molecular Formula: C25HNO7
• Molecular Weight: 467.59
• Purity: ≥95%
• Solubility: Easily soluble in chloroform, Moderately in methanol, Poorly soluble in acetone and ethanol
• Storage: Store at +4°C, in dark place.

LYCOCTONINE(cas 26000-17-9) is obtained from Aconitum lycoctonum and also from other species of Aconitum and Delphinium.


Diterpene Alkaloid.<!–C25HNO7–>The base alkaloid methyllicaconotine is isolated from Delfinium rotundifolium Afan. Plant (Ranunculaceae fam.)

It is a ganglion blocking agent, curare-like compound. It belongs to an original chemical class of reversible nicotinic receptors blocker

Reference

– Salimov, B. T.; Tashkhodzhaev, B.; Dzhakhangirov, F. N., /Structure and biologicalactivity of demethyleneldelidine and its dihydro-?-lactone/, Chemistry of Natural Compounds (2009) 45: 685-689 , November 24, 2009

– Salimov, B. T., /Alkaloids of Delphinium corymbosum/, Chemistry of Natural Compounds (2004) 40: 579-581 , November 01, 2004

– Boronova, Z. S.; Sultankhodzhaev, M. N., /Alkaloids of Delphinium poltoratskii/, Chemistry of Natural Compounds (2000) 36: 390-392 , July 01, 2000

– Dzhakhangirov, F. N.; Kasymova, K. R.; Sultankhodzhaev, M. N.; Salimov, B. T.; Usmanova, S. K.; Shakirov, R. Sh, /Toxicity and local anesthetic activity of diterpenoid alkaloids/, Chemistry of Natural Compounds (2007) 43: 581-589 , September 01, 2007

– Pelletier S., Mody N., Joshi S., Schramm L. In: Alkaloids: Chemical and biological perspectives. Ed. Pelletier S., Willey J. New-York, 1984, v.2, p. 418

– Dzhachangirov F., Salimov B., Bessoinova I., Sultankhodzhaev M. Search and study of curare-like drugs among diterpene alkaloids. Chim. Prirod. Soedin., 1995, No 6. p. (Rus.)