For research use only. Not for therapeutic Use.
Lyn-IN-1 (Cat.No:I005326) is a potent and selective inhibitor of Lyn kinase, a member of the Src family kinases (SFKs). Lyn-IN-1 has demonstrated promising anti-inflammatory and anti-cancer activities by targeting Lyn kinase-mediated signaling pathways. It shows potential as a therapeutic agent for the treatment of various diseases, including cancer and immune-related disorders.
| Catalog Number | I005326 |
| CAS Number | 887650-05-7 |
| Synonyms | 4-[[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl]-N-[4-methyl-3-[(5-pyrimidin-5-ylpyrimidin-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide |
| Molecular Formula | C30H31F3N8O |
| Purity | ≥95% |
| Target | Bcr-Abl |
| Solubility | 10 mM in DMSO |
| Storage | Store at -20℃ |
| IUPAC Name | 4-[[(3S)-3-(dimethylamino)pyrrolidin-1-yl]methyl]-N-[4-methyl-3-[(5-pyrimidin-5-ylpyrimidin-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide |
| InChI | InChI=1S/C30H31F3N8O/c1-19-4-7-24(11-27(19)39-29-36-14-23(15-37-29)22-12-34-18-35-13-22)38-28(42)20-5-6-21(26(10-20)30(31,32)33)16-41-9-8-25(17-41)40(2)3/h4-7,10-15,18,25H,8-9,16-17H2,1-3H3,(H,38,42)(H,36,37,39)/t25-/m0/s1 |
| InChIKey | ZOPBZHLJXQAQON-VWLOTQADSA-N |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CCC(C3)N(C)C)C(F)(F)F)NC4=NC=C(C=N4)C5=CN=CN=C5 |
| Reference | <p style=/line-height:25px/> </p> |
