Lys05

• CAT Number: I007861
• CAS Number: 1391426-24-6
• Molecular Formula: C23H26Cl5N5
• Molecular Weight: 549.75
• Purity: ≥95%
• Synonyms: LYS-05 HCl; LYS05; LYS-05; Lys01 (trihydrochloride); Lys01 HCl salt.;N2-(7-Chloro-4-quinolinyl)-N1-[2-[(7-chloro-4-quinolinyl)amino]ethyl]-N1-methyl-1,2-ethanediamine trihydrochloride
• Target: Autophagy
• Solubility: Soluble in DMSO and water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• Related CAS: 1391426-22-4(free base)
• IUPAC Name: N-(7-chloroquinolin-4-yl)-N'-[2-[(7-chloroquinolin-4-yl)amino]ethyl]-N'-methylethane-1,2-diamine;trihydrochloride
• InChI: InChI=1S/C23H23Cl2N5.3ClH/c1-30(12-10-28-20-6-8-26-22-14-16(24)2-4-18(20)22)13-11-29-21-7-9-27-23-15-17(25)3-5-19(21)23;;;/h2-9,14-15H,10-13H2,1H3,(H,26,28)(H,27,29);3*1H
• InChIKey: JTUYDBHQGOZPQQ-UHFFFAOYSA-N
• SMILES: CN(CCNC1=CC=NC2=CC(Cl)=CC=C12)CCNC3=CC=NC4=CC(Cl)=CC=C34.[H]Cl.[H]Cl.[H]Cl

Lys05 (CAT: I007861) is a novel lysosomal inhibitor that has shown promise in preclinical studies for the treatment of cancer. It acts by targeting lysosomes, which are cellular organelles involved in various physiological processes, including protein degradation and recycling. Lys05 inhibits lysosomal function, leading to the accumulation of damaged proteins and dysfunctional organelles, ultimately triggering cell death in cancer cells. It has demonstrated efficacy in various cancer models, including breast cancer, lung cancer, and pancreatic cancer. Lys05 is being investigated as a potential therapeutic agent for cancer treatment, and further research is ongoing to determine its safety, efficacy, and clinical applications.