For research use only. Not for therapeutic Use.
Lysostaphin（Cat No.:I014857）is an antibacterial enzyme derived from Staphylococcus simulans, known for its effectiveness against Staphylococcus aureus, including methicillin-resistant strains (MRSA). It works by cleaving the cross-links in the bacterial cell wall peptidoglycan, leading to cell lysis and death. In research, Lysostaphin is valuable for studying antimicrobial resistance, biofilm disruption, and alternative treatments for staphylococcal infections. Its potent and specific activity against S. aureus makes it a promising candidate in developing novel therapies for resistant bacterial infections and enhancing our understanding of bacterial cell wall integrity.
| Catalog Number | I014857 |
| CAS Number | 9011-93-2 |
| Purity | ≥95% |
| Target | Bacterial |
| IUPAC Name | 1-O-[2,6-dichloro-4-[[4-[[1-(2-cyanoacetyl)-4-methylpiperidin-3-yl]-methylamino]pyrrolo[2,3-d]pyrimidine-7-carbonyl]oxymethyl]phenyl] 9-O-[1,3-di(octadec-9-enoyloxy)propan-2-yl] 3,7-dimethylnonanedioate |
| InChI | InChI=1S/C74H112Cl2N6O11/c1-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-40-67(84)89-54-61(55-90-68(85)41-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-2)92-69(86)48-57(3)38-37-39-58(4)49-70(87)93-71-63(75)50-60(51-64(71)76)53-91-74(88)82-47-44-62-72(78-56-79-73(62)82)80(6)65-52-81(46-43-59(65)5)66(83)42-45-77/h21-24,44,47,50-51,56-59,61,65H,7-20,25-43,46,48-49,52-55H2,1-6H3 |
| InChIKey | JITWMWVPQUZNBO-UHFFFAOYSA-N |
| SMILES | CCCCCCCCC=CCCCCCCCC(=O)OCC(COC(=O)CCCCCCCC=CCCCCCCCC)OC(=O)CC(C)CCCC(C)CC(=O)OC1=C(C=C(C=C1Cl)COC(=O)N2C=CC3=C2N=CN=C3N(C)C4CN(CCC4C)C(=O)CC#N)Cl |
| Reference | [1]. Jaspal K Kumar, et al. Lysostaphin: An Antistaphylococcal Agent. Appl Microbiol Biotechnol. 2008 Sep;80(4):555-61. |
