For research use only. Not for therapeutic Use.
Lysyl hydroxylase 2-IN-1 (compound 12) is a selective lysyl hydroxylase 2 (LH2) Inhibitor with an IC50 of ~300 nM. Lysyl hydroxylase 2-IN-1 demonstrates selectivity for LH2 over LH1 and LH3[1].
| Catalog Number | I040722 |
| Synonyms | 1-(3-morpholin-4-ylphenyl)-3-pyridin-4-ylpropane-1,3-dione |
| Molecular Formula | C18H18N2O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H18N2O3/c21-17(14-4-6-19-7-5-14)13-18(22)15-2-1-3-16(12-15)20-8-10-23-11-9-20/h1-7,12H,8-11,13H2 |
| InChIKey | XWEDKEPGOROEEE-UHFFFAOYSA-N |
| SMILES | C1COCCN1C2=CC=CC(=C2)C(=O)CC(=O)C3=CC=NC=C3 |
| Reference | [1]. Juhoon Lee, et al. Unleashing the Potential of 1,3-Diketone Analogues as Selective LH2 Inhibitors. ACS Med Chem Lett. 2023, 14, 10, 1396-1403. |
