Lytixar

For research use only. Not for therapeutic Use.

  • CAT Number: I007897
  • CAS Number: 1166254-80-3
  • Molecular Formula: C43H69N11O3
  • Molecular Weight: 788.09
  • Purity: ≥95%
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Lytixar(Cat No.:I007897)is a selective and potent inhibitor of the Janus kinase (JAK) family of proteins, specifically JAK1 and JAK2, used in the treatment of autoimmune diseases. It modulates cytokine signaling pathways, reducing inflammation and immune cell activation. By inhibiting JAK-mediated signaling, Lytixar helps manage conditions like rheumatoid arthritis, psoriatic arthritis, and other inflammatory disorders. This targeted approach provides therapeutic benefits while minimizing systemic side effects. Lytixar is a key player in immunomodulation, promoting improved outcomes in patients with chronic inflammatory diseases.


Catalog Number I007897
CAS Number 1166254-80-3
Synonyms

Lytixar; LTX-109; LTX 109; LTX109.;(S)-2-amino-5-guanidino-N-((S)-1-(((S)-5-guanidino-1-oxo-1-(phenethylamino)pentan-2-yl)amino)-1-oxo-3-(2,5,7-tri-tert-butyl-1H-indol-3-yl)propan-2-yl)pentanamide

Molecular Formula C43H69N11O3
Purity ≥95%
Target Fungal
Solubility Soluble in DMSO
Storage 0 - 4 °C for short term, or -20 °C for long term
IUPAC Name (2S)-2-amino-5-(diaminomethylideneamino)-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxo-1-(2-phenylethylamino)pentan-2-yl]amino]-1-oxo-3-(2,5,7-tritert-butyl-1H-indol-3-yl)propan-2-yl]pentanamide
InChI InChI=1S/C43H69N11O3/c1-41(2,3)27-23-28-29(35(43(7,8)9)54-34(28)30(24-27)42(4,5)6)25-33(53-36(55)31(44)17-13-20-50-39(45)46)38(57)52-32(18-14-21-51-40(47)48)37(56)49-22-19-26-15-11-10-12-16-26/h10-12,15-16,23-24,31-33,54H,13-14,17-22,25,44H2,1-9H3,(H,49,56)(H,52,57)(H,53,55)(H4,45,46,50)(H4,47,48,51)/t31-,32-,33-/m0/s1
InChIKey ZVOYWSKEBVVLGW-ZDCRTTOTSA-N
SMILES CC(C)(C)C1=CC2=C(C(=C1)C(C)(C)C)NC(=C2C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCCC3=CC=CC=C3)NC(=O)[C@H](CCCN=C(N)N)N)C(C)(C)C

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