For research use only. Not for therapeutic Use.
m-PEG11-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Catalog Number | I016785 |
| CAS Number | 2168540-65-4 |
| Synonyms | 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol |
| Molecular Formula | C23H48O12 |
| Purity | ≥95% |
| InChI | InChI=1S/C23H48O12/c1-25-4-5-27-8-9-29-12-13-31-16-17-33-20-21-35-23-22-34-19-18-32-15-14-30-11-10-28-7-6-26-3-2-24/h24H,2-23H2,1H3 |
| InChIKey | VWDQSWKLHABGKL-UHFFFAOYSA-N |
| SMILES | COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
| Reference | [1]. Das A, et al. Consequences of Dispersity on the Self-Assembly of ABA-Type Amphiphilic Block Co-Oligomers. ACS Macro Lett. 2018 May 15;7(5):546-550. |
