For research use only. Not for therapeutic Use.
m-PEG11-Tos（Cat No.:I032725） is a polyethylene glycol (PEG) derivative that incorporates a tosyl group, known for its effectiveness as a leaving group in nucleophilic substitution reactions. The presence of the hydrophilic PEG spacer enhances the solubility of the compound in aqueous environments. This characteristic makes m-PEG11-Tos suitable for various applications in pharmaceutical and biotechnological research, such as drug delivery systems, bioconjugation, and surface modification of biomaterials.
| Catalog Number | I032725 |
| CAS Number | 58320-73-3 |
| Synonyms | m-PEG11-Tos |
| Molecular Formula | C28H50O13S |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 2,5,8,11,14,17,20,23,26,29-decaoxahentriacontan-31-yl 4-methylbenzenesulfonate |
| InChI | InChI=1S/C28H50O13S/c1-27-3-5-28(6-4-27)42(29,30)41-26-25-40-24-23-39-22-21-38-20-19-37-18-17-36-16-15-35-14-13-34-12-11-33-10-9-32-8-7-31-2/h3-6H,7-26H2,1-2H3 |
| InChIKey | PMVRKGLJXOGXGW-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(S(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)(=O)=O)C=C1 |
| Reference | 1: Brown A, Patel S, Ward C, Lorenz A, Ortiz M, DuRoss A, Wieghardt F, Esch A, Otten EG, Heiser LM, Korolchuk VI, Sun C, Sarkar S, Sahay G. PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder. Sci Rep. 2016 Aug 30;6:31750. doi: 10.1038/srep31750. PubMed PMID: 27572704; PubMed Central PMCID: PMC5004151. |
