For research use only, not for therapeutic use.
m-PEG12-OH (CAT: I016580) is a polyethylene glycol (PEG) based PROTAC linker that holds potential for use in the synthesis of PROTACs. Its unique structure allows for the conjugation of different molecular components, facilitating the creation of bifunctional molecules that can target specific proteins for degradation. This linker could play a crucial role in designing PROTACs, a class of molecules that utilize the body’s natural protein degradation machinery to selectively remove disease-causing proteins.
Catalog Number | I016580 |
CAS Number | 2050595-03-2 |
Molecular Formula | C₂₅H₅₂O₁₃ |
Purity | ≥95% |
Reference | [1]. Kachbi-Khelfallah S, et al. Towards potential nanoparticle contrast agents: Synthesis of new functionalized PEG bisphosphonates. Beilstein J Org Chem. 2016 Jul 4;12:1366-71.<br>[2]. Hamura, Mika, et al. Branched monodispersed polyethylene glycol, intermediate, and method for producing same. WO 2019181984 A1. |