For research use only. Not for therapeutic Use.
m-PEG3-Aminooxy is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Catalog Number | I014053 |
| CAS Number | 248275-10-7 |
| Synonyms | O-[2-[2-(2-methoxyethoxy)ethoxy]ethyl]hydroxylamine |
| Molecular Formula | C7H17NO4 |
| Purity | ≥95% |
| InChI | InChI=1S/C7H17NO4/c1-9-2-3-10-4-5-11-6-7-12-8/h2-8H2,1H3 |
| InChIKey | UPZRLQLRXOQKOM-UHFFFAOYSA-N |
| SMILES | COCCOCCOCCON |
| Reference | [1]. Luo W, et al. Tailored electroactive and quantitative ligand density microarrays applied to stem cell differentiation. J Am Chem Soc. 2010 Mar 3;132(8):2614-21. |
