For research use only. Not for therapeutic Use.
m-PEG3-OMs(CAT: I016015) serves as a PEG-based linker crucial for constructing PROTACs (PROteolysis Targeting Chimeras). In the intricate architecture of PROTACs, this linker enables the connection of distinct ligands—one designed for an E3 ubiquitin ligase and the other tailored for the target protein. This strategic bonding harnesses the cellular ubiquitin-proteasome system, orchestrating the targeted degradation of specific proteins.
| Catalog Number | I016015 |
| CAS Number | 74654-05-0 |
| Molecular Formula | C₈H₁₈O₆S |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
