m-PEG4-Boc

• CAT Number: I016450
• CAS Number: 883554-11-8
• Molecular Formula: C₁₄H₂₈O₆
• Molecular Weight: 292.37
• Purity: ≥95%
• Target: PROTAC
• IUPAC Name: tert-butyl 3-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C14H28O6/c1-14(2,3)20-13(15)5-6-17-9-10-19-12-11-18-8-7-16-4/h5-12H2,1-4H3
• InChIKey: JUINYDFUOXIVCX-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCOCCOCCOC

m-PEG4-Boc (Cat.No:I016450) is a polyethylene glycol derivative used in bioconjugation and drug delivery applications. It consists of a methoxy polyethylene glycol (m-PEG) chain with a tert-butyloxycarbonyl (Boc) protecting group. m-PEG4-Boc is commonly employed to modify biomolecules, such as proteins and peptides, to enhance their stability, solubility, and pharmacokinetic properties for therapeutic purposes.

Reference

[1]. Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.[2]. Peter Madsen, et al. Protease stabilized, pegylated insulin analogues. WO2009010428A1.