m-PEG4-sulfonic acid

For research use only. Not for therapeutic Use.

  • CAT Number: I016085
  • CAS Number: 787524-78-1
  • Molecular Formula: C9H20O7S
  • Molecular Weight: 272.32
  • Purity: ≥95%
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m-PEG4-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


Catalog Number I016085
CAS Number 787524-78-1
Synonyms

2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanesulfonic acid

Molecular Formula C9H20O7S
Purity ≥95%
InChI InChI=1S/C9H20O7S/c1-13-2-3-14-4-5-15-6-7-16-8-9-17(10,11)12/h2-9H2,1H3,(H,10,11,12)
InChIKey JOLNKYKZGYOWSY-UHFFFAOYSA-N
SMILES COCCOCCOCCOCCS(=O)(=O)O
Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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