For research use only. Not for therapeutic Use.
m-PEG5-CH2CH2COOH (CAT: I016709) is a PEG-based linker that finds application in the synthesis of PROTACs (PROteolysis TAgeting Chimeras). This linker is designed to connect a target protein-binding ligand to an E3 ligase-binding ligand, facilitating the formation of a PROTAC molecule. The linker consists of a polyethylene glycol (PEG) chain with five units, terminated by a carboxylic acid group (COOH) on one end and a reactive functional group on the other end.
Catalog Number | I016709 |
CAS Number | 1347750-72-4 |
Molecular Formula | C₁₄H₂₈O₈ |
Purity | ≥95% |
Target | PROTAC Linkers |
Reference | [1]. Parva Yogeshchandra Purohit, et al. Prodrugs of fulvestrant. WO2019224790A2. |