For research use only. Not for therapeutic Use.
m-PEG5-SH (CAT: I016300) is a PEG-based PROTAC linker designed for use in the synthesis of PROTAC molecules. This linker incorporates a PEG (polyethylene glycol) chain of five ethylene glycol units, which can provide water solubility and enhance the overall pharmacokinetic properties of the resulting PROTAC compound. The thiol (-SH) functional group at one end of the linker can serve as a reactive site for conjugation to other molecules or protein targets.
Catalog Number | I016300 |
CAS Number | 524030-00-0 |
Molecular Formula | C₁₁H₂₄O₅S |
Purity | ≥95% |
Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |