For research use only. Not for therapeutic Use.
m-PEG6-Br is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
| Catalog Number | I016461 |
| CAS Number | 125562-29-0 |
| Synonyms | 1-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]-2-methoxyethane |
| Molecular Formula | C13H27BrO6 |
| Purity | ≥95% |
| InChI | InChI=1S/C13H27BrO6/c1-15-4-5-17-8-9-19-12-13-20-11-10-18-7-6-16-3-2-14/h2-13H2,1H3 |
| InChIKey | GFRLIPYEIIWDJX-UHFFFAOYSA-N |
| SMILES | COCCOCCOCCOCCOCCOCCBr |
| Reference | [1]. Jennifer Riggs-Sauthier, et al. Oligomer-antihistamine conjugates. WO2008112257A1. |
