For research use only. Not for therapeutic Use.
M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1].
| Catalog Number | I031345 |
| CAS Number | 51314-51-3 |
| Synonyms | N-butyl-1H-benzimidazol-2-amine |
| Molecular Formula | C11H15N3 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H15N3/c1-2-3-8-12-11-13-9-6-4-5-7-10(9)14-11/h4-7H,2-3,8H2,1H3,(H2,12,13,14) |
| InChIKey | OKKUCNXCFWODOE-UHFFFAOYSA-N |
| SMILES | CCCCNC1=NC2=CC=CC=C2N1 |
| Reference | [1]. Ai-Jun Ding, et al. Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. Mol Cell Biochem. 2017 Feb;426(1-2):101-109. |
