For research use only. Not for therapeutic Use.
M190S(CAT: I040683) is a potent and selective DNA gyrase inhibitor that targets the GyrB subunit, disrupting bacterial DNA supercoiling, replication, and transcription. This small-molecule compound exhibits strong antibacterial activity, particularly against drug-resistant Gram-positive and Gram-negative bacteria, including strains resistant to fluoroquinolones. By interfering with a vital bacterial enzyme, M190S effectively halts bacterial proliferation. It is widely used in antibacterial research to investigate novel mechanisms of gyrase inhibition and to support the development of next-generation antibiotics. With its favorable potency and resistance profile, M190S represents a promising lead candidate for combating antibiotic-resistant infections and advancing antimicrobial therapy.
| CAS Number | 2578300-07-7 |
| Synonyms | N-[(1S)-1-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]ethyl]-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine |
| Molecular Formula | C21H21N5O2 |
| Purity | ≥95% |
| IUPAC Name | N-[(1S)-1-[4-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)phenyl]ethyl]-2,6-dimethylfuro[2,3-d]pyrimidin-4-amine |
| InChI | InChI=1S/C21H21N5O2/c1-11-10-17-19(23-13(3)24-21(17)27-11)22-12(2)14-4-8-16(9-5-14)20-25-18(26-28-20)15-6-7-15/h4-5,8-10,12,15H,6-7H2,1-3H3,(H,22,23,24)/t12-/m0/s1 |
| InChIKey | HKRGAACOQSQCIC-LBPRGKRZSA-N |
| SMILES | CC1=CC2=C(N=C(N=C2O1)C)NC(C)C3=CC=C(C=C3)C4=NC(=NO4)C5CC5 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
