mAChR-IN-1 hydrochloride

• CAT Number: I019168
• CAS Number: 119391-73-0
• Molecular Formula: C23H26ClIN2O2
• Molecular Weight: 524.82
• Purity: ≥95%
• Synonyms: 3-[1-[(4-iodophenyl)methyl]piperidin-4-yl]-3-phenylpiperidine-2,6-dione;hydrochloride
• InChI: InChI=1S/C23H25IN2O2.ClH/c24-20-8-6-17(7-9-20)16-26-14-11-19(12-15-26)23(18-4-2-1-3-5-18)13-10-21(27)25-22(23)28;/h1-9,19H,10-16H2,(H,25,27,28);1H
• InChIKey: LZPQCDPVLUEOSL-UHFFFAOYSA-N
• SMILES: C1CN(CCC1C2(CCC(=O)NC2=O)C3=CC=CC=C3)CC4=CC=C(C=C4)I.Cl

mAChR-IN-1 hydrochloride is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM[1].

Reference

[1]. Wilson AA, et al. Synthesis and biological evaluation of [125I]- and [123I]-4-iododexetimide, a potent muscarinic cholinergic receptor antagonist. J Med Chem. 1989 May;32(5):1057-62.
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