Magnesium L-Threonate

For research use only. Not for therapeutic Use.

  • CAT Number: I031464
  • CAS Number: 778571-57-6
  • Molecular Formula: C8H14MgO10
  • Molecular Weight: 294.5
  • Purity: 98%
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Magnesium L-Threonate(CAT: I031464) is a magnesium supplement that has gained attention for its potential cognitive benefits. Magnesium L-Threonate is a form of magnesium that is highly absorbable and can cross the blood-brain barrier, allowing it to potentially enhance brain function. Some studies suggest that it may improve memory and learning ability, as well as reduce symptoms of anxiety and depression.


Catalog Number I031464
CAS Number 778571-57-6
Synonyms

Magnesium L-Threonate

Molecular Formula C8H14MgO10
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name Magnesium (2R,3S)-2,3,4-trihydroxybutanoate
InChI InChI=1S/2C4H8O5.Mg/c2*5-1-2(6)3(7)4(8)9;/h2*2-3,5-7H,1H2,(H,8,9);/q;;+2/p-2/t2*2-,3+;/m00./s1
InChIKey YVJOHOWNFPQSPP-BALCVSAKSA-L
SMILES O=C([O-])[C@H](O)[C@@H](O)CO.O=C([O-])[C@H](O)[C@@H](O)CO.[Mg+2]
Reference

1: Xu T, Li D, Zhou X, Ouyang HD, Zhou LJ, Zhou H, Zhang HM, Wei XH, Liu G, Liu XG. Oral Application of Magnesium-L-Threonate Attenuates Vincristine-induced Allodynia and Hyperalgesia by Normalization of Tumor Necrosis Factor-α/Nuclear Factor-κB Signaling. Anesthesiology. 2017 Jun;126(6):1151-1168. doi: 10.1097/ALN.0000000000001601. PubMed PMID: 28306698.
2: Wang J, Liu Y, Zhou LJ, Wu Y, Li F, Shen KF, Pang RP, Wei XH, Li YY, Liu XG. Magnesium L-threonate prevents and restores memory deficits associated with neuropathic pain by inhibition of TNF-α. Pain Physician. 2013 Sep-Oct;16(5):E563-75. PubMed PMID: 24077207.
3: Mickley GA, Hoxha N, Luchsinger JL, Rogers MM, Wiles NR. Chronic dietary magnesium-L-threonate speeds extinction and reduces spontaneous recovery of a conditioned taste aversion. Pharmacol Biochem Behav. 2013 May;106:16-26. doi: 10.1016/j.pbb.2013.02.019. Epub 2013 Mar 6. PubMed PMID: 23474371; PubMed Central PMCID: PMC3668337.

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