For research use only. Not for therapeutic Use.
Mal-amide-PEG2-oxyamine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Mal-amide-PEG2-oxyamine Related Antibodies
| Catalog Number | I015290 |
| CAS Number | 2253965-09-0 |
| Synonyms | N-[2-[2-(2-aminooxyethoxy)ethoxy]ethyl]-3-(2,5-dioxopyrrol-1-yl)propanamide |
| Molecular Formula | C13H21N3O6 |
| Purity | ≥95% |
| InChI | InChI=1S/C13H21N3O6/c14-22-10-9-21-8-7-20-6-4-15-11(17)3-5-16-12(18)1-2-13(16)19/h1-2H,3-10,14H2,(H,15,17) |
| InChIKey | FNTXHRKNBBSZFH-UHFFFAOYSA-N |
| SMILES | C1=CC(=O)N(C1=O)CCC(=O)NCCOCCOCCON |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
