Mal-amido-PEG2-C2-acid

• CAT Number: I017202
• CAS Number: 756525-98-1
• Molecular Formula: C₁₄H₂₀N₂O₇
• Molecular Weight: 328.32
• Purity: ≥95%
• Target: PROTAC Linkers

Mal-amido-PEG2-C2-acid(CAT: I017202), also known as Maleimido-PEG2-C2-acid, is a compound containing a maleimide group, a polyethylene glycol (PEG) spacer, and a carboxylic acid group. Maleimide groups are commonly used for the modification and conjugation of biomolecules, such as proteins and peptides, through reaction with thiol groups. The PEG spacer provides flexibility and solubility to the molecule. Mal-amido-PEG2-C2-acid is often used as a building block in the synthesis of bioconjugates and drug delivery systems.

Reference

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.