For research use only. Not for therapeutic Use.
Mal-amido-PEG5-C2-NHS ester (CAT: I017853) is a PEG (polyethylene glycol) derivative that contains a maleimide (Mal) group, an amide linker, and a C2-NHS ester functional group. The maleimide group allows for specific conjugation with thiol-containing molecules, enabling the formation of stable thioether bonds. The amide linker provides flexibility, while the C2-NHS ester group allows for conjugation with primary amine groups. This compound is commonly used in bioconjugation and drug delivery applications, where it can be employed to modify and functionalize biomolecules, such as proteins and peptides, for various purposes including targeted drug delivery, imaging, and diagnostics.
| Catalog Number | I017853 |
| CAS Number | 1315355-92-0 |
| Molecular Formula | C₂₄H₃₅N₃O₁₂ |
| Purity | ≥95% |
| Target | ADC Linker |
| Reference | [1]. Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145.<br>[2]. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A |
