Mal-C5-N-bis(PEG2-C2-acid)

For research use only. Not for therapeutic Use.

  • CAT Number: I040191
  • CAS Number: 3026691-12-0
  • Molecular Formula: C24H38N2O11
  • Molecular Weight: 530.57
  • Purity: ≥95%
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Mal-C5-N-bis(PEG2-C2-acid) (Cat No.: I040191) is a chemical compound designed for use in bioconjugation and drug delivery applications. It features a maleimide group (Mal) for thiol-specific conjugation, a C5 linker, and two PEG2-C2-acid units, which provide solubility and enhance pharmacokinetics. This structure is useful for linking proteins, antibodies, or other biomolecules to therapeutic agents or diagnostic tools, improving their stability and targeting efficiency. Its applications include developing targeted therapies for diseases such as cancer or for enhancing molecular imaging techniques.


CAS Number 3026691-12-0
Synonyms

3-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethyl-[6-(2,5-dioxopyrrol-1-yl)hexanoyl]amino]ethoxy]ethoxy]propanoic acid

Molecular Formula C24H38N2O11
Purity ≥95%
IUPAC Name 3-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethyl-[6-(2,5-dioxopyrrol-1-yl)hexanoyl]amino]ethoxy]ethoxy]propanoic acid
InChI InChI=1S/C24H38N2O11/c27-20(4-2-1-3-9-26-21(28)5-6-22(26)29)25(10-14-36-18-16-34-12-7-23(30)31)11-15-37-19-17-35-13-8-24(32)33/h5-6H,1-4,7-19H2,(H,30,31)(H,32,33)
InChIKey OCGSASUSCDQIMT-UHFFFAOYSA-N
SMILES C1=CC(=O)N(C1=O)CCCCCC(=O)N(CCOCCOCCC(=O)O)CCOCCOCCC(=O)O
Reference

[1]. Mark Frigerio, et al. The Chemical Design and Synthesis of Linkers Used in Antibody Drug Conjugates. Curr Top Med Chem. 2017;17(32):3393-3424.
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