Mal-C5-N-bis(PEG2-C2-acid)

• CAT Number: I040191
• CAS Number: 3026691-12-0
• Molecular Formula: C24H38N2O11
• Molecular Weight: 530.57
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethyl-[6-(2,5-dioxopyrrol-1-yl)hexanoyl]amino]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C24H38N2O11/c27-20(4-2-1-3-9-26-21(28)5-6-22(26)29)25(10-14-36-18-16-34-12-7-23(30)31)11-15-37-19-17-35-13-8-24(32)33/h5-6H,1-4,7-19H2,(H,30,31)(H,32,33)
• InChIKey: OCGSASUSCDQIMT-UHFFFAOYSA-N
• SMILES: C1=CC(=O)N(C1=O)CCCCCC(=O)N(CCOCCOCCC(=O)O)CCOCCOCCC(=O)O

Mal-C5-N-bis(PEG2-C2-acid) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Reference

[1]. Mark Frigerio, et al. The Chemical Design and Synthesis of Linkers Used in Antibody Drug Conjugates. Curr Top Med Chem. 2017;17(32):3393-3424.
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